If you love bold flavors, creamy sauces, and a little Southern spice, these Cajun Chicken Lasagna Roll Ups are about to become your new favorite comfort food! Picture tender lasagna noodles rolled up with juicy Cajun-seasoned chicken, a creamy cheese filling, and a rich, smoky sauce. It’s a fun twist on classic lasagna with a little Louisiana flair. Whether you’re cooking for a weeknight dinner or impressing guests, this dish is a total showstopper!
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Why You’ll Love Cajun Chicken Lasagna Roll Ups
Packed with Flavor: The perfect balance of creamy, cheesy goodness and bold Cajun spices.
Easy to Serve: Individual roll-ups make portioning a breeze—no messy slicing required!
Great for Meal Prep: Make them ahead of time and pop them in the oven when you’re ready to eat.
Customizable: Adjust the spice level to your liking or swap out ingredients to fit your taste.
Comfort Food with a Kick: It’s rich, satisfying, and just spicy enough to keep things exciting.
Ingredients in Cajun Chicken Lasagna Roll Ups
Lasagna Noodles: The foundation of the roll-ups—soft, tender, and perfect for holding all that cheesy goodness.
Chicken Breast: Seasoned with Cajun spices and cooked until juicy and flavorful. You can also use rotisserie chicken for an easy shortcut!
Cajun Seasoning: A blend of spices that brings smoky, spicy, and bold flavors to every bite.
Ricotta Cheese: Creamy and light, it helps bind the filling together.
Mozzarella Cheese: Melts beautifully for that gooey, stretchy cheese factor.
Parmesan Cheese: Adds a nutty, salty depth to the filling and sauce.
Heavy Cream: Creates a rich, velvety sauce that coats each roll-up perfectly.
Garlic: A must-have for depth and aroma.
Butter: Adds richness to the sauce and enhances the flavors.
Chicken Broth: Helps create a silky sauce without making it too heavy.
Green Onions & Parsley: Fresh garnishes that balance out the richness of the dish.
Instructions
Cook the Noodles: Boil lasagna noodles until al dente, then drain and lay them flat on a parchment-lined surface to prevent sticking.
Prepare the Chicken: Season the chicken with Cajun seasoning and cook in a skillet until golden brown and fully cooked. Let it rest, then shred or dice into bite-sized pieces.
Make the Filling: In a bowl, mix ricotta cheese, shredded mozzarella, Parmesan, cooked chicken, and a pinch of Cajun seasoning. Stir until well combined.
Assemble the Roll Ups: Spread a layer of the cheese mixture onto each lasagna noodle, then roll them up tightly and place them seam-side down in a greased baking dish.
Make the Sauce: In a pan, melt butter and sauté garlic until fragrant. Pour in chicken broth and heavy cream, then whisk in more Cajun seasoning and Parmesan cheese. Simmer until thickened.
Bake to Perfection: Pour the sauce over the roll-ups, top with extra mozzarella, and bake at 375°F (190°C) for 20-25 minutes until bubbly and golden.
Garnish and Serve: Sprinkle with chopped green onions and parsley for a fresh finish. Serve hot and enjoy!
How to Serve Cajun Chicken Lasagna Roll Ups
With Garlic Bread: The perfect way to soak up all that creamy, spicy sauce.
With a Crisp Salad: A simple green salad with a tangy vinaigrette balances out the richness.
With Roasted Vegetables: Try roasted bell peppers, zucchini, or asparagus for a flavorful side.
As a Standalone Dish: These roll-ups are filling enough to enjoy on their own!
Additional Tips
Make It Spicier: Add cayenne pepper or extra Cajun seasoning for a fiery kick.
Use Rotisserie Chicken: Save time by using pre-cooked rotisserie chicken instead of cooking your own.
Make It Ahead: Assemble the roll-ups and store them in the fridge overnight before baking.
Freeze for Later: Freeze unbaked roll-ups in an airtight container. Bake straight from frozen, adding a few extra minutes to the cooking time.
Lighten It Up: Use half-and-half instead of heavy cream and swap ricotta for cottage cheese for a lighter version.
FAQ Section
Q1: Can I make this dish ahead of time?
A1: Yes! Assemble the roll-ups and refrigerate them for up to 24 hours before baking.
Q2: Can I use store-bought Alfredo sauce instead of making my own?
A2: Absolutely! If you’re short on time, a jar of Alfredo sauce works as a quick substitute.
Q3: How do I store leftovers?
A3: Keep leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven or microwave.
Q4: Can I freeze this dish?
A4: Yes! Freeze before or after baking. If freezing before, bake straight from frozen with extra time added.
Q5: What’s the best way to reheat lasagna roll-ups?
A5: Reheat in the oven at 350°F (175°C) until warmed through, or microwave in short intervals.
Q6: Can I use a different type of cheese?
A6: Yes! Try pepper jack for extra spice or provolone for a creamy, mild flavor.
Q7: What if I don’t have Cajun seasoning?
A7: You can make your own with paprika, garlic powder, onion powder, cayenne, oregano, thyme, salt, and pepper.
Q8: Can I make this without dairy?
A8: Use dairy-free cheese alternatives and coconut cream instead of heavy cream for a lactose-free version.
Q9: Can I add vegetables to the filling?
A9: Definitely! Sautéed bell peppers, spinach, or mushrooms would be great additions.
Q10: How can I make this dish vegetarian?
A10: Swap the chicken for sautéed mushrooms or a mix of roasted vegetables and use vegetable broth for the sauce.
This Cajun Chicken Lasagna Roll Ups recipe is comfort food with a kick! Cheesy, creamy, and packed with bold flavors, it’s the perfect way to spice up your dinner routine. Give it a try and enjoy every bite!
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Cajun Chicken Lasagna Roll Ups
- Yield: 6 servings 1x
- Category: Dinner
- Method: Baking
- Cuisine: Cajun
Description
These Cajun Chicken Lasagna Roll Ups are a flavorful twist on classic lasagna! Tender lasagna noodles are filled with Cajun-spiced chicken, ricotta, spinach, and sun-dried tomatoes, then rolled up and baked in a creamy Cajun Alfredo sauce. Perfect for a cozy weeknight dinner!
Ingredients
Lasagna Roll-Ups
- 12 lasagna noodles
- 1 lb cooked chicken breast, diced (or shredded rotisserie chicken)
- 1 block cream cheese, softened
- 1 1/2 cups ricotta cheese
- 2/3 cup frozen chopped spinach, defrosted and drained
- 4 oz sun-dried tomatoes, chopped
- 1 tbsp Cajun seasoning (store-bought or homemade, see below)
- 2 1/2 cups shredded cheddar/mozzarella cheese, divided
Cajun Alfredo Sauce
- 4 tbsp butter
- 4 cloves garlic, minced
- 1 cup heavy cream
- 1 tbsp Cajun seasoning
- Salt and pepper, to taste
- 1/2 cup grated Parmesan
Homemade Cajun Seasoning (Optional)
- 2 tbsp paprika
- 3/4 tsp salt
- 2 tsp garlic powder
- 2 tsp onion powder
- 2 tsp chili powder
- 1 1/2 tsp dried thyme
- 1 tsp dried oregano
- 1 tsp brown sugar
- 3/4 tsp cayenne pepper (adjust to taste)
- 1/2 tsp black pepper
Instructions
- Preheat oven to 375°F (190°C) and grease a 9×13 baking dish.
- In a large bowl, mix ricotta and cream cheese until smooth. Fold in sun-dried tomatoes, spinach, Cajun seasoning, chicken, and 1 cup of shredded cheese until well combined.
- Cook lasagna noodles to al dente according to package instructions. Drain and lay flat.
- While noodles cook, make the Cajun Alfredo sauce:
- Melt butter in a saucepan over medium-low heat.
- Add garlic and sauté until fragrant.
- Stir in heavy cream, Cajun seasoning, and Parmesan. Simmer for 5-6 minutes, stirring occasionally, until slightly thickened.
- Spread a few spoonfuls of Alfredo sauce on the bottom of the baking dish.
- Assemble the roll-ups:
- Spread ⅔ cup of filling onto one end of each lasagna noodle.
- Roll tightly and place seam-side down in the dish.
- Repeat with remaining noodles.
- Pour Alfredo sauce evenly over the lasagna rolls, spooning any extra sauce back on top.
- Sprinkle 1½ cups of shredded cheese over the rolls.
- Bake uncovered for 35 minutes, or until edges are crispy and cheese is golden brown.
- Let cool for 5 minutes before serving.
Nutrition
- Serving Size: 1 serving
- Calories: 570
- Sugar: 4g
- Sodium: 920mg
- Fat: 38g
- Saturated Fat: 20g
- Unsaturated Fat: 15 g
- Trans Fat: 0g
- Carbohydrates: 30g
- Fiber: 3g
- Protein: 35g
- Cholesterol: 135mg